MedCourseFinder

Hepatology

MELD (original, UNOS)

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Formula

MELD = round(10 x [0.957 ln Cr + 0.378 ln bilirubin + 1.120 ln INR + 0.643]); values below 1 set to 1; Cr maximum 4.0 (4.0 if on dialysis); maximum 40.

Limitations

  • Superseded for US allocation by MELD-Na (2016) and MELD 3.0 (2023); MELD 3.0 is not implemented here.
  • Rounding conventions vary (UNOS rounds MELD(i) to tenths in some documents); this implementation rounds the final x10 value once.

References

  1. A model to predict survival in patients with end-stage liver disease. Kamath PS, Wiesner RH, Malinchoc M, et al. Hepatology. 2001;33(2):464-470. PMID 11172350
  2. A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Malinchoc M, Kamath PS, Gordon FD, et al. Hepatology. 2000;31(4):864-871. PMID 10733541